A comparative study on two pituitrin injection methods in laparoscopic salpingotomy for tubal pregnancy

Background: Tubal pregnancy is a common gynecological acute abdomen, and is often treated by laparoscopic salpingotomy. This study aimed to compare two pituitrin injection methods in laparoscopic salpingotomy for tubal pregnancy. Methods: 200 patients with unruptured tubal pregnancy were randomly divided into observation group 1, observation group 2 and control group. Before laparoscopic salpingotomy, the patients in observation group 1 and 2 were injected with pituitrin at corpus uteri and mesosalpinx, respectively. The control group did not use pituitrin injection. The intraoperative and postoperative conditions and postoperative tubal patency and pregnancy among three groups were compared. Results: The intraoperative blood losses in observation groups 1 and 2 were significantly less than control group (P < 0.05), and the operation durations in observation groups 1 and 2 were significantly shorter than control group (P < 0.05). The postoperative persistent ectopic pregnancy rates in observation groups 1 and 2 were significantly lower than control group (P < 0.05). After operation, the tubal patency rates and intrauterine pregnancy rates in observation group 1 and observation group 2 were significant higher than control group (P < 0.05), and the recurrent ectopic pregnancy rates in observation groups 1 and 2 were significantly lower than control group (P < 0.01). There was no significant difference of above indexes between two observation groups (P > 0.05). Conclusions: For patients with tubal pregnancy, both injection of pituitrin at corpus uteri and mesosalpinx during laparoscopic salpingotomy can reduce the blood loss and operation duration, and improve the tubal patency and intrauterine pregnancy rates.